Pan-RAS-IN-1
Pan-RAS-IN-1, a pan-Ras inhibitor, binds to KRasG12D-GppNHp with a Kd less than 20 μM in MST, ITC and NMR assays, also binds to Ras proteins and exhibits lethality in cells partially dependent on expression of Ras proteins.
| Catalog Number | E1157 |
| Molecular Formula | C36H41Cl2F3N6O2 |
| CAS# | 1835283-94-7 |
| SMILES | NC1(CCNCC1)C(=O)NCCC[N]2C=C(C3=CC=C(OC(F)(F)F)C=C3)C4=C2C=CC(=C4)CN5CCN(CC5)CC6=C(Cl)C=CC=C6Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pan-ras-in-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e1157-pan-ras-in-1-chemical-structure.gif |