Erlotinib
Erlotinib is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Erlotinib induces autophagy.
| Trivial name | CP358774, NSC 718781,OSI-774 |
| Catalog Number | S7786 |
| Molecular Formula | C22H23N3O4 |
| CAS# | 183321-74-6 |
| Inchi | InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25) |
| Inchi Key | AAKJLRGGTJKAMG-UHFFFAOYSA-N |
| SMILES | COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC |
| Size | 200mg |
| Supplier Page | http://www.selleckchem.com/products/erlotinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/erlotinib-free-base-chemical-structure-s7786.gif |