2-BP (2-Bromohexadecanoic acid)
2-BP (2-Bromohexadecanoic acid) is a nonmetabolisable analogue of palmitate and acts as a palmitoylation inhibitor, which inhibits multiple palmitoyl-acyl transferase (PAT) activity towards MyrGCK(NBD) and FarnCNRas(NBD) with identical IC50s of approx. 4 µM. 2-Bromohexadecanoic acid can directly and irreversibly inhibit the palmitoyltransferase activity of all DHHC (Asp-His-His-Cys) proteins.
Trivial name | 2-bromopalmitate |
Catalog Number | E0120 |
Molecular Formula | C16H31BrO2 |
CAS# | 18263-25-7 |
SMILES | CCCCCCCCCCCCCCC(Br)C(O)=O |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/2-bromohexadecanoic-acid.html |
Additional Information | https://file.selleck.cn/downloads/struct/e0120-2-bromohexadecanoic-acid-chemical-structure.gif |