GGTI298
GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC50 values of 3 and > 20 μM in vivo, respectively.
| Catalog Number | E7318 |
| Molecular Formula | C9H14N4O5 |
| CAS# | 180977-44-0 |
| Inchi | InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1 |
| Inchi Key | RTRQQBHATOEIAF-UUOKFMHZSA-N |
| SMILES | C1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ggti298.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7318-ggti298-chemical-structure-tube.png |