FTI 277 HCl
FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.
| Trivial name | N/A |
| Catalog Number | S7465 |
| Molecular Formula | C22H30ClN3O3S2 |
| CAS# | 180977-34-8 |
| Inchi | InChI=1S/C22H29N3O3S2.ClH/c1-28-22(27)20(10-11-30-2)25-21(26)18-9-8-17(24-13-16(23)14-29)12-19(18)15-6-4-3-5-7-15;/h3-9,12,16,20,24,29H,10-11,13-14,23H2,1-2H3,(H,25,26);1H/t16-,20+;/m1./s1 |
| Inchi Key | PIAFFJUUNXEDEW-PXPMWPIZSA-N |
| SMILES | COC(=O)C(CCSC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2.Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/fti-277-hcl.html |
| Additional Information | https://file.selleck.cn/downloads/struct/fti-277-hcl-chemical-structure-s7465.gif |