ONC212
ONC212, a fluorinated-ONC201 analogue, is a selective agonist of GPR132. ONC212 is broadly efficacious across most solid tumors and hematological malignancies in the low nanomolar range and has robust anti-leukemic activity.
Trivial name | N/A |
Catalog Number | S8673 |
Molecular Formula | C24H23F3N4O |
CAS# | 1807861-48-8 |
Inchi | InChI=1S/C24H23F3N4O/c25-24(26,27)19-8-6-18(7-9-19)15-31-22(32)20-16-29(14-17-4-2-1-3-5-17)12-10-21(20)30-13-11-28-23(30)31/h1-9H,10-16H2 |
Inchi Key | DFULPGUTXZTYKA-UHFFFAOYSA-N |
SMILES | C1CN(CC2=C1N3CCN=C3N(C2=O)CC4=CC=C(C=C4)C(F)(F)F)CC5=CC=CC=C5 |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/onc212.html |
Additional Information | https://file.selleck.cn/downloads/struct/onc212-chemical-structure-s8673.gif |