PF-06952229

PF-06952229(UNII-1KKS7U3X86) is a selective, orally available inhibitor of the serine/threonine kinase TGF-β receptor 1 (TGF-β-R1). It inhibits pSMAD2 in both tumor and immune cells, reducing TGF-β signalling and reversing EMT in vitro. It modulates the tumor immune microenvironment and shows antitumor activity in mouse models.

Price Not Available 25mg PF-06952229 Supplier Page

Trivial name	UNII-1KKS7U3X86
Catalog Number	E1785
Molecular Formula	C8H11NO3.ClH
CAS#	1801333-55-0
Size	25mg
Supplier Page	http://www.selleckchem.com/products/pf-06952229.html
Additional Information	https://file.selleck.cn/downloads/struct/E1785-PF-06952229-chemical-structure.png