Borussertib
Borussertib is a covalent-allosteric inhibitor of protein kinase Akt with an IC50 of 0.8 nM and a Ki of 2.2 nM for WT Akt.
| Trivial name | N/A |
| Catalog Number | S8839 |
| Molecular Formula | C36H32N6O3 |
| CAS# | 1800070-77-2 |
| Inchi | InChI=1S/C36H32N6O3/c1-2-33(43)38-26-12-13-31-32(20-26)42(36(45)40-31)27-15-18-41(19-16-27)22-23-8-10-25(11-9-23)34-28(24-6-4-3-5-7-24)21-29-30(39-34)14-17-37-35(29)44/h2-14,17,20-21,27H,1,15-16,18-19 ,22H2,(H,37,44)(H,38,43)(H,40,45) |
| Inchi Key | HXBRBOYWXDLHDC-UHFFFAOYSA-N |
| SMILES | C=CC(=O)NC1=CC2=C(C=C1)NC(=O)N2C3CCN(CC3)CC4=CC=C(C=C4)C5=C(C=C6C(=N5)C=CNC6=O)C7=CC=CC=C7 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/borussertib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/borussertib-chemical-structure-s8839.gif |