Lanraplenib (GS-SYK)
Lanraplenib (GS-SYK)is a potent, highly selective and orally active inhibitor of Spleen Tyrosine Kinase (SYK) with IC50 of 9.5 nM. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.
| Trivial name | GS-9876 |
| Catalog Number | S9715 |
| Molecular Formula | C23H25N9O |
| CAS# | 1800046-95-0 |
| SMILES | NC1=CN=CC(=N1)C2=C[N]3C=CN=C3C(=N2)NC4=CC=C(C=C4)N5CCN(CC5)C6COC6 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/lanraplenib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s9715-gs-9876-lanraplenib--chemical-structure.gif |