S63845
S63845 is a new, selective MCL-1 inhibitor with the Kd value of 0.19 nM and has no discernible binding to the other BCL-2 members, BCL-2 or BCL-XL.
| Trivial name | N/A |
| Catalog Number | S8383 |
| Molecular Formula | C39H37ClF4N6O6S |
| CAS# | 1799633-27-4 |
| Inchi | InChI=1S/C39H37ClF4N6O6S/c1-23-26(7-8-28(34(23)40)53-18-17-49-15-13-48(2)14-16-49)32-33-36(45-22-46-37(33)57-35(32)29-9-10-31(41)55-29)56-30(38(51)52)19-24-5-3-4-6-27(24)54-20-25-11-12-47-50(25)21-39( 42,43)44/h3-12,22,30H,13-21H2,1-2H3,(H,51,52)/t30-/m1/s1 |
| Inchi Key | ZFBHXVOCZBPADE-SSEXGKCCSA-N |
| SMILES | CC1=C(C=CC(=C1Cl)OCCN2CCN(CC2)C)C3=C(SC4=NC=NC(=C34)OC(CC5=CC=CC=C5OCC6=CC=NN6CC(F)(F)F)C(=O)O)C7=CC=C(O7)F |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/s63845.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s63845-chemical-structure-s8383.gif |