MIK665 (S64315)
MIK665 (S64315) is an inhibitor of induced myeloid leukemia cell differentiation protein Mcl-1 with Ki value of 1.2 nM and has potential pro-apoptotic and antineoplastic activities.
| Trivial name | N/A |
| Catalog Number | S8836 |
| Molecular Formula | C47H44ClFN6O6S |
| CAS# | 1799631-75-6 |
| Inchi | InChI=1S/C47H44ClFN6O6S/c1-29-34(16-17-38(42(29)48)59-25-24-55-22-20-54(2)21-23-55)40-41-45(51-28-52-46(41)62-43(40)30-12-14-32(49)15-13-30)61-39(47(56)57)26-31-8-4-6-10-36(31)60-27-33-18-19-50-44(53- 33)35-9-5-7-11-37(35)58-3/h4-19,28,39H,20-27H2,1-3H3,(H,56,57)/t39-/m0/s1 |
| Inchi Key | PKYIMGFMRFVOMB-KDXMTYKHSA-N |
| SMILES | CC1=C(C=CC(=C1Cl)OCCN2CCN(CC2)C)C3=C(SC4=NC=NC(=C34)OC(CC5=CC=CC=C5OCC6=NC(=NC=C6)C7=CC=CC=C7OC)C(=O)O)C8=CC=C(C=C8)F |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/s64315-mik665.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s64315-mik665-s-64315-chemical-structure-s8836.gif |