Tolinapant (ASTX660)
Tolinapant (ASTX660) is a potent, non-peptidomimetic antagonist of cIAP1/2 and XIAP that inhibits the interactions between a SMAC-derived peptide and the BIR3 domains of XIAP (BIR3-XIAP) and cIAP1 (BIR3-cIAP1) with IC50 values less than 40 and 12 nmol/L, respectively.
| Trivial name | N/A |
| Catalog Number | S8681 |
| Molecular Formula | C30H42FN5O3 |
| CAS# | 1799328-86-1 |
| SMILES | CC1CN(C(CN1)CN2CCOCC2C)CC(=O)N3CC(C4=C3C=C(C(=N4)CO)CC5=CC=C(C=C5)F)(C)C |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/astx660.html |
| Additional Information | https://file.selleck.cn/downloads/struct/astx660-chemical-structure-s8681.gif |