GSK J4 HCl
GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM in a cell-free assay and inactive against a panel of demethylases of the JMJ family.
| Catalog Number | S7070 |
| Molecular Formula | C24H27N5O2.HCl |
| CAS# | 1797983-09-5 |
| Inchi | InChI=1S/C24H27N5O2.ClH/c1-2-31-23(30)10-14-26-21-17-22(28-24(27-21)20-9-5-6-13-25-20)29-15-11-18-7-3-4-8-19(18)12-16-29;/h3-9,13,17H,2,10-12,14-16H2,1H3,(H,26,27,28);1H |
| Inchi Key | TYXWLTBYINKVNT-UHFFFAOYSA-N |
| SMILES | CCOC(=O)CCNC1=CC(=NC(=N1)C2=CC=CC=N2)N3CCC4=CC=CC=C4CC3.Cl |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/gsk-j4-hcl.html |
| Additional Information | https://file.selleck.cn/downloads/struct/GSK-J4-HCL-chemical-structure-s7070.gif |