MZ-1
MZ-1 is a PROTAC degrader of bromodomain-containing protein 4 (BRD4). MZ-1 binds to the Brd bromodomain with Kd of 62 nM, 60 nM, 21 nM, 13 nM, 39 nM and 15 nM for Brd2BD1, Brd2BD2, Brd3BD1, Brd3BD2, Brd4BD1 and Brd4BD2.
| Trivial name | N/A |
| Catalog Number | S8889 |
| Molecular Formula | C49H60ClN9O8S2 |
| CAS# | 1797406-69-9 |
| SMILES | CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NCCOCCOCCOCC(=O)NC(C(=O)N4CC(CC4C(=O)NCC5=CC=C(C=C5)C6=C(N=CS6)C)O)C(C)(C)C)C7=CC=C(C=C7)Cl)C |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/mz-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s8889-mz-1-chemical-structure.gif |