MZ-1
MZ-1 is a PROTAC degrader of bromodomain-containing protein 4 (BRD4). MZ-1 binds to the Brd bromodomain with Kd of 62 nM, 60 nM, 21 nM, 13 nM, 39 nM and 15 nM for Brd2BD1, Brd2BD2, Brd3BD1, Brd3BD2, Brd4BD1 and Brd4BD2.
Trivial name | N/A |
Catalog Number | S8889 |
Molecular Formula | C49H60ClN9O8S2 |
CAS# | 1797406-69-9 |
SMILES | CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NCCOCCOCCOCC(=O)NC(C(=O)N4CC(CC4C(=O)NCC5=CC=C(C=C5)C6=C(N=CS6)C)O)C(C)(C)C)C7=CC=C(C=C7)Cl)C |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/mz-1.html |
Additional Information | https://file.selleck.cn/downloads/struct/s8889-mz-1-chemical-structure.gif |