Ritlecitinib (PF-06651600)

Ritlecitinib (PF-06651600) is a potent and irreversible JAK3-selective inhibitor with an IC50 of 33.1 nM but without activity (IC50 > 10 000 nM) against JAK1, JAK2, and TYK2.

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Trivial name	N/A
Catalog Number	S8538
Molecular Formula	C15H19N5O
CAS#	1792180-81-4
Inchi	InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
Inchi Key	CBRJPFGIXUFMTM-WDEREUQCSA-N
SMILES	CC1CCC(CN1C(=O)C=C)NC2=NC=NC3=C2C=CN3
Size	1g
Supplier Page	http://www.selleckchem.com/products/pf-06651600.html
Additional Information	https://file.selleck.cn/downloads/struct/pf-06651600-chemical-structure-s8538.gif