NVS-PAK1-1
NVS-PAK1-1 is a potent allosteric inhibitor of p21-activated kinase PAK1, a serine-threonine kinase that is upregulated in many cancers. NVS-PAK1-1 has an IC50 value of 5 nM for dephoshorylated PAK1 and 6 nM for phosphorylated PAK1 in an in vitro dephosphorylation assay.
| Trivial name | / |
| Catalog Number | CSN20017 |
| Alternative Name(s) | / |
| Research Area | Cancer |
| Molecular Formula | C23H25ClF3N5O |
| CAS# | 1783816-74-9 |
| Purity | ≥98% |
| SMILES | O=C(N1C[C@@H](NC2=NC3=CC(F)=CC=C3N(CC(F)F)C4=CC=C(Cl)C=C42)CC1)NC(C)C |
| Size | 1mg |
| Supplier Page | https://www.csnpharm.com/products/nvs-pak1-1.html |