Desmethylglycitein

Desmethylglycitein (4′,6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity. Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1). Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes.

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Trivial name	4',6,7-Trihydroxyisoflavone
Catalog Number	E7438
Molecular Formula	C24H29N5O3
CAS#	17817-31-1
Inchi	InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1
Inchi Key	ACWBQPMHZXGDFX-QFIPXVFZSA-N
SMILES	CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)O
Size	5mg
Supplier Page	http://www.selleckchem.com/products/desmethylglycitein.html
Additional Information	https://file.selleck.cn/downloads/struct/e7438-desmethylglycitein-chemical-structure-tube.png