PP2
PP2 (AG 1879, AGL 1879), a Src family kinase inhibitor, potently inhibits Lck/Fyn with IC50 of 4 nM/5 nM in cell-free assays, ~100-fold less potent to EGFR, inactive for ZAP-70, JAK2 and PKA.
| Trivial name | AG 1879,AGL 1879 |
| Catalog Number | S7008 |
| Molecular Formula | C15H16ClN5 |
| CAS# | 172889-27-9 |
| Inchi | InChI=1S/C15H16ClN5/c1-15(2,3)21-14-11(13(17)18-8-19-14)12(20-21)9-4-6-10(16)7-5-9/h4-8H,1-3H3,(H2,17,18,19) |
| Inchi Key | PBBRWFOVCUAONR-UHFFFAOYSA-N |
| SMILES | CC(C)(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)Cl)N |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/pp2.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PP2-chemical-structure-s7008.gif |