Zegocractin (CM 4620)
Zegocractin (CM 4620) is an inhibitor of calcium-release activated calcium-channel (CRAC channel). CM4620 inhibits Orai1/STIM1-mediated Ca2+ currents and Orai2/STIM1-mediated currents with IC50 of near 120 nM and 900 nM, respectively.
| Trivial name | N/A |
| Catalog Number | S6834 |
| Molecular Formula | C19H11ClF3N3O3 |
| CAS# | 1713240-67-5 |
| SMILES | CC1=C(C(=CC=C1)F)C(=O)NC2=NC=C(N=C2)C3=CC4=C(C=C3Cl)OC(O4)(F)F |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/cm-4620.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s6834-cm-4620-chemical-structure.gif |