Aprepitant
Aprepitant is a potent and selective neurokinin-1 receptor antagonist with IC50 of 0.1 nM. Aprepitant reduces levels of pro-inflammatory cytokines including G-CSF, IL-6, IL-8 and TNFα. Aprepitant inhibits HIV infection of human macrophages.
| Trivial name | MK-0869, L-754030 |
| Catalog Number | S1189 |
| Molecular Formula | C17H20N6O2S |
| CAS# | 170729-80-3 |
| SMILES | CC(C)(C1=CC2=C(S1)C(=NC(=N2)C3=CN=C(N=C3)N)N4CCOCC4)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/Aprepitant.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Aprepitant-MK-0869-chemical-structure-S1189.gif |