Aprepitant
Aprepitant is a potent and selective neurokinin-1 receptor antagonist with IC50 of 0.1 nM. Aprepitant reduces levels of pro-inflammatory cytokines including G-CSF, IL-6, IL-8 and TNFα. Aprepitant inhibits HIV infection of human macrophages.
| Trivial name | MK-0869, L-754030 |
| Catalog Number | S1189 |
| Molecular Formula | C9H6OS3 |
| CAS# | 170729-80-3 |
| Inchi | InChI=1S/C9H6OS3/c10-7-3-1-6(2-4-7)8-5-9(11)13-12-8/h1-5,10H |
| Inchi Key | IWBBKLMHAILHAR-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C2=CC(=S)SS2)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/Aprepitant.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Aprepitant-MK-0869-chemical-structure-S1189.gif |