Fisogatinib (BLU-554)
Fisogatinib (BLU-554) is a potent, highly-selective, oral FGFR4 inhibitor with an IC50 value of 5 nM. The IC50s for FGFR1-3 is 624-2203 nM.
| Trivial name | N/A |
| Catalog Number | S8503 |
| Molecular Formula | C24H24Cl2N4O4 |
| CAS# | 1707289-21-1 |
| Inchi | InChI=1S/C24H24Cl2N4O4/c1-4-20(31)28-16-7-8-34-12-17(16)30-24-27-11-14-9-13(5-6-15(14)29-24)21-22(25)18(32-2)10-19(33-3)23(21)26/h4-6,9-11,16-17H,1,7-8,12H2,2-3H3,(H,28,31)(H,27,29,30)/t16-,17+/m0/s1 |
| Inchi Key | MGZKYOAQVGSSGC-DLBZAZTESA-N |
| SMILES | COC1=CC(=C(C(=C1Cl)C2=CC3=CN=C(N=C3C=C2)NC4COCCC4NC(=O)C=C)Cl)OC |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/blu-554.html |
| Additional Information | https://file.selleck.cn/downloads/struct/blu-554-chemical-structure-S8503.gif |