Imidafenacin
Imidafenacin (KRP-197, ONO-8025) is a urinary antispasmodic of the anticholinergic class. It is a novel antimuscarinic agent with safety and efficacy, has been clinically used for the treatment of overactive bladder. Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors(IC50=4.13 nM). IC50 value: 0.3 nM(M3).
| Trivial name | KRP-197, ONO-8025 |
| Catalog Number | S5385 |
| Molecular Formula | C20H21N3O |
| CAS# | 170105-16-5 |
| Inchi | InChI=1S/C20H21N3O/c1-16-22-13-15-23(16)14-12-20(19(21)24,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11,13,15H,12,14H2,1H3,(H2,21,24) |
| Inchi Key | SQKXYSGRELMAAU-UHFFFAOYSA-N |
| SMILES | CC1=NC=CN1CCC(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/imidafenacin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/imidafenacin-chemical-structure-s5385.gif |