ARS-1620
ARS-1620 is a potent, orally bioavailable covalent inhibitor of KRASG12C and could achieve rapid and sustained in vivo target occupancy to induce tumor regression.
| Trivial name | N/A |
| Catalog Number | S8707 |
| Molecular Formula | C21H17ClF2N4O2 |
| CAS# | 1698055-85-4 |
| Inchi | InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17(19(24)20(12)25-11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2 |
| Inchi Key | ZRPZPNYZFSJUPA-UHFFFAOYSA-N |
| SMILES | C=CC(=O)N1CCN(CC1)C2=NC=NC3=C(C(=C(C=C32)Cl)C4=C(C=CC=C4F)O)F |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/ars-1620.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ars-1620-chemical-structure-s8707.gif |