Eganelisib (IPI-549)
Eganelisib (IPI-549) is a potent inhibitor of PI3K-γ with >100-fold selectivity over other lipid and protein kinases. The biochemical IC50 for PI3K-γ is 16 nM.
Trivial name | N/A |
Catalog Number | S8330 |
Molecular Formula | C30H24N8O2 |
CAS# | 1693758-51-8 |
Inchi | InChI=1S/C30H24N8O2/c1-19(34-29(39)26-27(31)35-37-15-7-14-32-28(26)37)24-16-22-9-6-8-21(13-12-20-17-33-36(2)18-20)25(22)30(40)38(24)23-10-4-3-5-11-23/h3-11,14-19H,1-2H3,(H2,31,35)(H,34,39)/t19-/m0/s1 |
Inchi Key | XUMALORDVCFWKV-IBGZPJMESA-N |
SMILES | CC(C1=CC2=C(C(=CC=C2)C#CC3=CN(N=C3)C)C(=O)N1C4=CC=CC=C4)NC(=O)C5=C6N=CC=CN6N=C5N |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/ipi-549.html |
Additional Information | https://file.selleck.cn/downloads/struct/ipi-549-chemical-structure-S8330.gif |