Su1498

Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.

Price Not Available 50 mg Su1498 Supplier Page
Catalog Number T3980
Alternative Name(s) Tyrphostin SU 1498 , AG 1498
Research Area Tyrosine Kinase/Adaptors|||Angiogenesis
Molecular Formula C25H30N2O2
CAS# 168835-82-3
Purity 99.54%
SMILES CC(C)c1cc(cc(C(C)C)c1O)\C=C(/C#N)C(=O)NCCCc1ccccc1
Size 50 mg
Supplier Page https://www.targetmol.com/compound/Su1498
Additional Information https://www.targetmol.com/datasheet/T3980