5-Ph-IAA
The 5-Ph-IAA is a bumped-IAA analogue, that establishes the auxin-inducible degron 2 (AID2) system with the OsTIR1(F74G) mutant, enabling precise, rapid degradation with 670-fold lower ligand concentration. It induces rapid and efficient depletion of mAID-fused proteins to study protein function in living cells, exhibiting significant tumor suppression properties.
| Catalog Number | E8177 |
| Molecular Formula | C9H10O3 |
| CAS# | 168649-23-8 |
| Inchi | InChI=1S/C9H10O3/c1-6(10)8-4-3-7(12-2)5-9(8)11/h3-5,11H,1-2H3 |
| Inchi Key | UILPJVPSNHJFIK-UHFFFAOYSA-N |
| SMILES | CC(=O)C1=C(C=C(C=C1)OC)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/5-ph-iaa.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E8177-5-Ph-IAA-chemical-structure.png |