5-Ph-IAA
The 5-Ph-IAA is a bumped-IAA analogue, that establishes the auxin-inducible degron 2 (AID2) system with the OsTIR1(F74G) mutant, enabling precise, rapid degradation with 670-fold lower ligand concentration. It induces rapid and efficient depletion of mAID-fused proteins to study protein function in living cells, exhibiting significant tumor suppression properties.
| Catalog Number | E8177 |
| Molecular Formula | C15H14O5 |
| CAS# | 168649-23-8 |
| Inchi | InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2 |
| Inchi Key | VGEREEWJJVICBM-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/5-ph-iaa.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E8177-5-Ph-IAA-chemical-structure.png |