Fosbretabulin Disodium
Fosbretabulin disodium is the water-soluble prodrug of Combretastatin A4 (CA4), which is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM in a cell-free assay. Fosbretabulin disodium inhibits the polymerization of tubulin with IC50 of 2.4 μM, and also disrupts tumor vasculature.
| Trivial name | Fosbretabulin Disodium Salt; CA-4P; Combretastatin-A4 Disodium Phosphate |
| Catalog Number | CSN12790 |
| Alternative Name(s) | Fosbretabulin Disodium Salt; CA-4P; Combretastatin-A4 Disodium Phosphate |
| Research Area | Cancer |
| Molecular Formula | C18H19Na2O8P |
| CAS# | 168555-66-6 |
| Purity | ≥99% |
| SMILES | O=P([O-])([O-])OC1=CC(/C=C\C2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC.[Na+].[Na+] |
| Size | 5mg |
| Supplier Page | https://www.csnpharm.com/products/fosbretabulin-disodium.html |