PD98059
PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM in a cell-free assay, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR) and functions as an AHR antagonist.
| Trivial name | N/A |
| Catalog Number | S1177 |
| Molecular Formula | C16H13NO3 |
| CAS# | 167869-21-8 |
| Inchi | InChI=1S/C16H13NO3/c1-19-14-8-4-6-11(16(14)17)15-9-12(18)10-5-2-3-7-13(10)20-15/h2-9H,17H2,1H3 |
| Inchi Key | QFWCYNPOPKQOKV-UHFFFAOYSA-N |
| SMILES | COC1=CC=CC(=C1N)C2=CC(=O)C3=CC=CC=C3O2 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/PD-98059.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PD98059-chemical-structure-S1177.gif |