PD98059
PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM in a cell-free assay, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR) and functions as an AHR antagonist.
| Trivial name | N/A |
| Catalog Number | S1177 |
| Molecular Formula | C16H13ClN4 |
| CAS# | 167869-21-8 |
| Inchi | InChI=1S/C16H13ClN4/c17-13-4-1-10(2-5-13)14-7-12(9-21-16(14)19)11-3-6-15(18)20-8-11/h1-9H,(H2,18,20)(H2,19,21) |
| Inchi Key | KHPCIHZXOGHCLY-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C2=C(N=CC(=C2)C3=CN=C(C=C3)N)N)Cl |
| Size | 200mg |
| Supplier Page | http://www.selleckchem.com/products/PD-98059.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PD98059-chemical-structure-S1177.gif |