Doxepin
Doxepin (MF 10) is a potent inhibitor of serotonin reuptake and noradrenaline reuptake with a Ki of 68 nM and 29.5 nM, respectively. It acts as a receptor antagonist for histamine H1, acetylcholine muscarinic, and α1 adrenoceptor with a Ki of 0.24 nM, 83 nM, and 24 nM, respectively and significantly inhibits CYP450.
| Catalog Number | E7725 |
| Molecular Formula | C13H16N2.HCl |
| CAS# | 1668-19-5 |
| Inchi | InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1 |
| Inchi Key | VPNGEIHDPSLNMU-MERQFXBCSA-N |
| SMILES | CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C.Cl |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/doxepin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E7725-Doxepin-chemical-structure.png |