Avasimibe
Avasimibe inhibits ACAT with IC50 of 3.3 μM, also inhibits human P450 isoenzymes CYP2C9, CYP1A2 and CYP2C19 with IC50 of 2.9 μM, 13.9 μM and 26.5 μM, respectively.
| Trivial name | CI-1011, PD-148515 |
| Catalog Number | S2187 |
| Molecular Formula | C16H21ClIN3O4S |
| CAS# | 166518-60-1 |
| Inchi | InChI=1S/C16H21ClIN3O4S/c1-3-26(23,24)20-11-4-6-21(7-5-11)16(22)10-19-14-9-13(18)12(17)8-15(14)25-2/h3,8-9,11,19-20H,1,4-7,10H2,2H3 |
| Inchi Key | ZGUSBCDCZNBNQT-UHFFFAOYSA-N |
| SMILES | COC1=CC(=C(C=C1NCC(=O)N2CCC(CC2)NS(=O)(=O)C=C)I)Cl |
| Size | 200mg |
| Supplier Page | http://www.selleckchem.com/products/Avasimibe(CI-1011).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Avasimibe-CI-1011-chemical-structure-S2187.gif |