Avasimibe
Avasimibe inhibits ACAT with IC50 of 3.3 μM, also inhibits human P450 isoenzymes CYP2C9, CYP1A2 and CYP2C19 with IC50 of 2.9 μM, 13.9 μM and 26.5 μM, respectively.
| Trivial name | CI-1011, PD-148515 |
| Catalog Number | S2187 |
| Molecular Formula | C29H43NO4S |
| CAS# | 166518-60-1 |
| Inchi | InChI=1S/C29H43NO4S/c1-17(2)22-14-25(20(7)8)27(26(15-22)21(9)10)16-28(31)30-35(32,33)34-29-23(18(3)4)12-11-13-24(29)19(5)6/h11-15,17-21H,16H2,1-10H3,(H,30,31) |
| Inchi Key | PTQXTEKSNBVPQJ-UHFFFAOYSA-N |
| SMILES | CC(C)C1=C(C(=CC=C1)C(C)C)OS(=O)(=O)NC(=O)CC2=C(C=C(C=C2C(C)C)C(C)C)C(C)C |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/Avasimibe(CI-1011).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Avasimibe-CI-1011-chemical-structure-S2187.gif |