Avasimibe
Avasimibe inhibits ACAT with IC50 of 3.3 μM, also inhibits human P450 isoenzymes CYP2C9, CYP1A2 and CYP2C19 with IC50 of 2.9 μM, 13.9 μM and 26.5 μM, respectively.
| Trivial name | CI-1011, PD-148515 |
| Catalog Number | S2187 |
| Molecular Formula | C36H46N8O3 |
| CAS# | 166518-60-1 |
| Inchi | InChI=1S/C36H46N8O3/c1-4-47-32-23-25(34(45)43-17-15-26(16-18-43)42-21-19-40(2)20-22-42)13-14-29(32)38-36-37-24-31-33(39-36)44(27-9-5-6-10-27)30-12-8-7-11-28(30)35(46)41(31)3/h7-8,11-14,23-24,26-27H,4- 6,9-10,15-22H2,1-3H3,(H,37,38,39) |
| Inchi Key | XVBGRTMNFNMINE-UHFFFAOYSA-N |
| SMILES | CCOC1=C(C=CC(=C1)C(=O)N2CCC(CC2)N3CCN(CC3)C)NC4=NC=C5C(=N4)N(C6=CC=CC=C6C(=O)N5C)C7CCCC7 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Avasimibe(CI-1011).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Avasimibe-CI-1011-chemical-structure-S2187.gif |