PZ-1922 free base | MedChemExpress (MCE)
PZ-1922 free base is a BBB-penetrable 5-HT6R/5-HT3R antagonist (Ki: 17 nM, 0.45 nM for 5-HT6R/5-HT3R respectively). PZ-1922 free base reversibly inhibits MAO-B (pIC50: 8.93). PZ-1922 free base reverses Scopolamine (SCOP) (HY-N0296) induced memory deficits in the novel object recognition (NOR) test in rats. PZ-1922 free base prevents Aβ-induced memory decline in the T-maze test[1].
| Trivial name | PZ-1922 free base |
| Catalog Number | HY-155330A |
| Research Area | Neurological Disease |
| CAS# | 1648745-65-6 |
| Purity | ≥98.0% |
| SMILES | ClC1=CC=CC(CN2C=CC3=C2C4=C(C=CC=C4)N=C3N5CCNCC5)=C1 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/pz-1922-free-base.html |