Oclacitinib maleate
Oclacitinib maleate (PF-03394197) is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM. It does not inhibit a panel of 38 non-JAK kinases.
Trivial name | PF-03394197 |
Catalog Number | S8195 |
Molecular Formula | C15H23N5O2S.C4H4O4 |
CAS# | 1640292-55-2 |
Inchi | InChI=1S/C15H23N5O2S.C4H4O4/c1-16-23(21,22)9-11-3-5-12(6-4-11)20(2)15-13-7-8-17-14(13)18-10-19-15;5-3(6)1-2-4(7)8/h7-8,10-12,16H,3-6,9H2,1-2H3,(H,17,18,19);1-2H,(H,5,6)(H,7,8)/b;2-1-/t11-,12-; |
Inchi Key | VQIGDTLRBSNOBV-VQIYXBGXSA-N |
SMILES | CNS(=O)(=O)CC1CCC(CC1)N(C)C2=NC=NC3=C2C=CN3.C(=CC(=O)O)C(=O)O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/oclacitinib-maleate.html |
Additional Information | https://file.selleck.cn/downloads/struct/oclacitinib-maleate-chemical-structure-s8195.gif |