Esaxerenone (CS-3150)
Esaxerenone (CS-3150), a selective nonsteroidal mineralocorticoid receptor (MR) antagonist, binds to mineralocorticoid receptor and inhibits (3)H-aldosterone binding to mineralocorticoid receptor with an IC50 value of 9.4 nM. Esaxerenone (CS-3150) also has the property of increasing the likelihood of albuminuria returning to normal levels and reducing progression of albuminuria to higher levels.
| Catalog Number | E0704 |
| Molecular Formula | C22H21F3N2O4S |
| CAS# | 1632006-28-0 |
| SMILES | CC1=C([N](CCO)C=C1C(=O)NC2=CC=C(C=C2)[S](C)(=O)=O)C3=CC=CC=C3C(F)(F)F |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/esaxerenone.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e0704-esaxerenone-chemical-structure.gif |