ARS-853
ARS-853 is a selective, covalent KRAS(G12C) inhibitor that inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation. ARS-853 also induces apoptosis.
| Trivial name | N/A |
| Catalog Number | S8156 |
| Molecular Formula | C22H29ClN4O3 |
| CAS# | 1629268-00-3 |
| Inchi | InChI=1S/C22H29ClN4O3/c1-3-20(29)27-13-15(14-27)25-6-8-26(9-7-25)21(30)12-24-18-10-16(22(2)4-5-22)17(23)11-19(18)28/h3,10-11,15,24,28H,1,4-9,12-14H2,2H3 |
| Inchi Key | IPFOCHMOYUMURK-UHFFFAOYSA-N |
| SMILES | CC1(CC1)C2=CC(=C(C=C2Cl)O)NCC(=O)N3CCN(CC3)C4CN(C4)C(=O)C=C |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/ars-853.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ARS-853-chemical-structure-S8156.gif |