INCB054329
INCB054329 is a structurally distinct bromodomain and extraterminal domain (BET) inhibitor with IC50 values of 44 nM, 5 nM, 9 nM, 1 nM, 28 nM, 3 nM, 119 nM and 63 nM for BRD2-BD1, BRD2-BD2, BRD3-BD1, BRD3-BD2, BRD4-BD1, BRD4-BD2, BRDT-BD1 and BRDT-BD2, respectively.
| Catalog Number | S8753 |
| Molecular Formula | C19H16N4O3 |
| CAS# | 1628607-64-6 |
| Inchi | InChI=1S/C19H16N4O3/c1-10-16(11(2)26-22-10)12-6-7-14-17-18(12)25-9-15(23(17)19(24)21-14)13-5-3-4-8-20-13/h3-8,15H,9H2,1-2H3,(H,21,24)/t15-/m1/s1 |
| Inchi Key | XYLPKCDRAAYATL-OAHLLOKOSA-N |
| SMILES | CC1=C(C(=NO1)C)C2=C3C4=C(C=C2)NC(=O)N4C(CO3)C5=CC=CC=N5 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/incb054329.html |
| Additional Information | https://file.selleck.cn/downloads/struct/incb054329-chemical-structure-s8753.gif |