GSK467
GSK467 is a cell penetrant and selective inhibitor of KDM5B (JARID1B/PLU1) with Ki of 10 nM. GSK467 shows apparent 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other JmJ family members.
| Trivial name | N/A |
| Catalog Number | S0269 |
| Molecular Formula | C17H13N5O2 |
| CAS# | 1628332-52-4 |
| Inchi | InChI=1S/C17H13N5O2/c23-16-14-6-7-18-9-15(14)20-17(21-16)24-13-8-19-22(11-13)10-12-4-2-1-3-5-12/h1-9,11H,10H2,(H,20,21,23) |
| Inchi Key | ZTYRLXUTLYBVHH-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)CN2C=C(C=N2)OC3=NC4=C(C=CN=C4)C(=O)N3 |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/gsk467.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gsk467-chemical-structure-s0269.gif |