Pico145
Pico145(HC-608) is a selective inhibitor of TRPC1/4/5 channels. It inhibits (−)-englerin A-activated TRPC4/TRPC5 channels, with IC50 values of 0.349 and 1.3 nM, respectively. It exhibits no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.
| Trivial name | HC-608 |
| Catalog Number | E4648 |
| Molecular Formula | C21H18BrNO3 |
| CAS# | 1628287-16-0 |
| SMILES | CC(=O)C1=CC2=C(C=C1)NC(C3C2C=CC3)C4=CC5=C(C=C4Br)OCO5 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pico145.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4648-Pico145-chemical-structure.png |