Pico145

Pico145(HC-608) is a selective inhibitor of TRPC1/4/5 channels. It inhibits (−)-englerin A-activated TRPC4/TRPC5 channels, with IC50 values of 0.349 and 1.3 nM, respectively. It exhibits no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.

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Trivial name	HC-608
Catalog Number	E4648
Molecular Formula	C15H8F2LiN5O3
CAS#	1628287-16-0
SMILES	[Li]OC(=O)C1=C(NC(=O)C2=NN=C(C=C2)[N]3C=CN=C3)C=C(F)C(=C1)F
Size	1g
Supplier Page	http://www.selleckchem.com/products/pico145.html
Additional Information	https://file.selleck.cn/downloads/struct/E4648-Pico145-chemical-structure.png