G1T38
G1T38 (Lerociclib) is a novel, potent, selective, and orally bioavailable CDK4/6 inhibitor with IC50 values of 0.001 μM, 0.002 μM and 0.028 μM for CDK4, CDK6 and CDK9 respectively.
| Trivial name | Lerociclib |
| Catalog Number | S8568 |
| Molecular Formula | C26H34N8O |
| CAS# | 1628256-23-4 |
| Inchi | InChI=1S/C26H34N8O/c1-18(2)32-10-12-33(13-11-32)20-6-7-22(27-16-20)30-25-28-15-19-14-21-24(35)29-17-26(8-4-3-5-9-26)34(21)23(19)31-25/h6-7,14-16,18H,3-5,8-13,17H2,1-2H3,(H,29,35)(H,27,28,30,31) |
| Inchi Key | YPJRHEKCFKOVRT-UHFFFAOYSA-N |
| SMILES | CC(C)N1CCN(CC1)C2=CN=C(C=C2)NC3=NC=C4C=C5C(=O)NCC6(N5C4=N3)CCCCC6 |
| Size | 2mg |
| Supplier Page | http://www.selleckchem.com/products/g1t38.html |
| Additional Information | https://file.selleck.cn/downloads/struct/g1t38-chemical-structure-s8568.gif |