KDM5-IN-1
KDM5-IN-1 is a potent, selective and orally bioavailable inhibitor of KDM5 with an IC50 value of 15.1 nM. It displays an increased cell potency with an EC50 value of 0.34 μM, respectively.
| Catalog Number | E7827 |
| Molecular Formula | C24H16F6N6O |
| CAS# | 1628210-26-3 |
| Inchi | InChI=1S/C24H16F6N6O/c1-36-19-7-6-15(10-17(19)34-22(36)33-14-4-2-13(3-5-14)23(25,26)27)37-16-8-9-31-18(11-16)21-32-12-20(35-21)24(28,29)30/h2-12H,1H3,(H,32,35)(H,33,34) |
| Inchi Key | YABJJWZLRMPFSI-UHFFFAOYSA-N |
| SMILES | CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/kdm5-in-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E7827-KDM5-IN-1-chemical-structure.png |