AZD3759 hydrochloride
AZD3759 (hydrochloride) is an effective, orally active and central nervous system-penetrant EGFR inhibitor. At Km ATP concentrations, the IC50s are 0.2/0.3/0.2 nM for EGFR (L858R)/EGFR (wt)/EGFR (exon 19Del).
| Catalog Number | T4249 |
| Research Area | Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors |
| Molecular Formula | C22H24Cl2FN5O3 |
| CAS# | 1626387-81-2 |
| SMILES | C[C@@H]1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C.Cl |
| Size | 5 mg |
| Supplier Page | https://www.targetmol.com/compound/AZD3759 hydrochloride |
| Additional Information | https://www.targetmol.com/datasheet/T4249 |