Temsirolimus
Temsirolimus is a specific mTOR inhibitor with IC50 of 1.76 μM in a cell-free assay. Temsirolimus induces autophagy and apoptosis.
| Trivial name | NSC 683864,CCI-779 |
| Catalog Number | S1044 |
| Molecular Formula | C56H87NO16 |
| CAS# | 162635-04-3 |
| Inchi | InChI=1S/C56H87NO16/c1-33-17-13-12-14-18-34(2)45(68-9)29-41-22-20-39(7)56(67,73-41)51(63)52(64)57-24-16-15-19-42(57)53(65)71-46(30-43(60)35(3)26-38(6)49(62)50(70-11)48(61)37(5)25-33)36(4)27-40-21-23-4 4(47(28-40)69-10)72-54(66)55(8,31-58)32-59/h12-14,17-18,26,33,35-37,39-42,44-47,49-50,58-59,62,67H,15-16,19-25,27-32H2,1-11H3/b14-12+,17-13+,34-18+,38-26+/t33-,35-,36-,37-,39-,40+,41+,42+,44-,45+,46+, 47-,49-,50+,56-/m1/s1 |
| Inchi Key | CBPNZQVSJQDFBE-FUXHJELOSA-N |
| SMILES | CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC |
| Size | 200mg |
| Supplier Page | http://www.selleckchem.com/products/Temsirolimus.html |
| Additional Information | https://file.selleck.cn/downloads/struct/temsirolimus-cci-779-nsc-683864-chemical-structure-s1044.gif |