Salirasib
Salirasib (Farnesylthiosalicylic acid, FTS) is a potent competitive prenylated protein methyltransferase (PPMTase) inhibitor with Ki of 2.6 μM, which inhibits Ras methylation. Salirasib exerts antitumor effects and induces autophagy. Phase 2.
Trivial name | Farnesylthiosalicylic acid, FTS |
Catalog Number | S7684 |
Molecular Formula | C22H30O2S |
CAS# | 162520-00-5 |
Inchi | InChI=1S/C22H30O2S/c1-17(2)9-7-10-18(3)11-8-12-19(4)15-16-25-21-14-6-5-13-20(21)22(23)24/h5-6,9,11,13-15H,7-8,10,12,16H2,1-4H3,(H,23,24)/b18-11+,19-15+ |
Inchi Key | WUILNKCFCLNXOK-CFBAGHHKSA-N |
SMILES | CC(=CCCC(=CCCC(=CCSC1=CC=CC=C1C(=O)O)C)C)C |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/salirasib.html |
Additional Information | https://file.selleck.cn/downloads/struct/salirasib-chemical-structure-s7684.gif |