GSK2982772
GSK2982772 is an ATP competitive receptor-interacting protein-1 (RIP1) kinase (RIPK1) inhibitor with the IC50 value of 16 nM. It has exquisite kinase specificity and excellent activity in blocking many TNF-dependent cellular responses.
Trivial name | N/A |
Catalog Number | S8484 |
Molecular Formula | C20H19N5O3 |
CAS# | 1622848-92-3 |
Inchi | InChI=1S/C20H19N5O3/c1-25-15-9-5-6-10-16(15)28-12-14(20(25)27)21-19(26)18-22-17(23-24-18)11-13-7-3-2-4-8-13/h2-10,14H,11-12H2,1H3,(H,21,26)(H,22,23,24)/t14-/m0/s1 |
Inchi Key | LYPAFUINURXJSG-AWEZNQCLSA-N |
SMILES | CN1C2=CC=CC=C2OCC(C1=O)NC(=O)C3=NNC(=N3)CC4=CC=CC=C4 |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/gsk2982772.html |
Additional Information | https://file.selleck.cn/downloads/struct/GSK2982772-chemical-structure-S8484.gif |